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  • Title: Motor neuron disease: a chemical perspective.
    Author: Wood LK, Langford SJ.
    Journal: J Med Chem; 2014 Aug 14; 57(15):6316-31. PubMed ID: 24694032.
    Abstract:
    This Perspective provides a background to the pathogenesis of neurodegenerative disease and specifically amyotrophic lateral sclerosis (ALS) and gives an overview of the many pathways, both genetically inheritable and sporadic, that may lead to the premature activation of apoptotic pathways in neurons, as well as current and proposed approaches toward interrupting these pathways.
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