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  • Title: Prospective study of Hepatitis E Virus infection among pregnant women in France.
    Author: Renou C, Gobert V, Locher C, Moumen A, Timbely O, Savary J, Roque-Afonso AM, Association Nationale des Hépato-Gastroentérologues des Hôpitaux Généraux (ANGH).
    Journal: Virol J; 2014 Apr 09; 11():68. PubMed ID: 24716485.
    Abstract:
    BACKGROUND: Hepatitis E Virus (HEV) infection has a poor prognosis among pregnant women from high endemic countries. HEV-prevalence and incidence among pregnant women is unknown in high-income countries such as France. This prospective study was conducted to assess HEV infection in this setting. FINDINGS: An overall HEV prevalence of 7.74% was observed among 315 pregnant women. Seroprevalence was higher in south than in north of France (29.3% vs. 3.6%, p < 0.0001), and women with detectable IgG were older. No IgG seroconversion or IgM detection were observed during pregnancy. CONCLUSIONS: Data suggest that HEV infection is a rare occurrence during pregnancy even in regions of western countries with high seroprevalence rates.
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