These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The spore coat of a fucosylation mutant in Dictyostelium discoideum.
    Author: Gonzalez-Yanes B, Mandell RB, Girard M, Henry S, Aparicio O, Gritzali M, Brown RD, Erdos GW, West CM.
    Journal: Dev Biol; 1989 Jun; 133(2):576-87. PubMed ID: 2471657.
    Abstract:
    Strain HL250 of Dictyostelium discoideum cannot convert GDP-mannose to GDP-fucose, resulting in an inability to fucosylate protein. This affects a group of proteins which are normally fucosylated intracellularly and then secreted via prespore vesicles to become part of the outer lamina of the spore coat. We have found that strain HL250 nevertheless accumulates typical amounts of these proteins, stores them normally in prespore vesicles, and secretes them normally to become a part of the spore coat. However, affected proteins are proteolyzed after germination, the spore coat is more accessible to penetration by a macromolecular probe, and germination is inefficient in older spores. These findings can be explained by a dependence of the integrity of the outer layer of the spore coat on protein-linked fucose.
    [Abstract] [Full Text] [Related] [New Search]