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  • Title: Prognostic value of abdominal sonography in necrotizing enterocolitis of premature infants born before 33 weeks gestational age.
    Author: Garbi-Goutel A, Brévaut-Malaty V, Panuel M, Michel F, Merrot T, Gire C.
    Journal: J Pediatr Surg; 2014 Apr; 49(4):508-13. PubMed ID: 24726102.
    Abstract:
    OBJECTIVE: The purpose of this study was to assess the prognostic value of abdominal sonography in necrotizing enterocolitis (NEC) in preterm infants with a gestational age less than 33 weeks of gestation, using surgery and/or death as the primary outcome and stenosis as the secondary outcome. METHODS: A retrospective study of 95 premature infants (mean gestational age: 28.6 weeks), presenting with NEC between January 2009 and November 2011 and who underwent plain abdominal radiography and sonography, was performed. In uni- and multivariate analyses, radiographic and sonographic findings were correlated with complications ('surgery and/or death' and 'stenosis'). RESULTS: Sonographic findings of free intraperitoneal air (odd ratio [OR]=8.0; IC, 1.4-44.2), free abdominal fluid (OR 3.5; IC 1.3-9.4), portal venous gas (OR 3.9; IC, 1.2-12.9), and bowel wall thickening (OR 2.8; IC,1.1-7.2) were significantly associated with surgery and/or death. Intramural gas was significantly correlated (OR=11.8; IC, 1.5-95.8) with intestinal stenosis following NEC. None of the radiographic findings were associated with complications. CONCLUSION: Abdominal sonography is a reliable tool for the prognostic assessment of NEC in preterm infants.
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