These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Predictive value of one-dimensional mean computed tomography value of ground-glass opacity on high-resolution images for the possibility of future change.
    Author: Tamura M, Shimizu Y, Yamamoto T, Yoshikawa J, Hashizume Y.
    Journal: J Thorac Oncol; 2014 Apr; 9(4):469-72. PubMed ID: 24736068.
    Abstract:
    OBJECTIVES: The purpose of this study was to evaluate the relationship between clinical and radiological findings and the progression of ground-glass opacity (GGO) and to identify risk factors that predict the outcome of pure GGO lesions. METHODS: A retrospective study was conducted on 63 nodules of pure GGO. Clinical characteristics, the largest diameter, shape, and marginal characteristics, and one-dimensional mean computed tomography (m-CT) value of the GGO lesions were evaluated. During follow-up, 12 GGO lesions increased in size, and 17 appeared as solid portion. These 29 lesions were classified as growth group, and the remaining 34 lesions as stable group. RESULTS: The m-CT values were -634.9 ± 15.3 and -712.1 ± 14.1 HU for the growth and stable groups, respectively. The growth group was strongly associated with high m-CT values (p = 0.0007) and a history of lung cancer (p = 0.0389), whereas association with smoking habits and the shape of the GGO nodules was marginal. The m-CT values and a history of lung cancer were independent predictors for future changes in GGO lesions (p = 0.0023 and p = 0.0129, respectively). Sixteen of 18 lesions (88.9%) in patients without a history of lung cancer and with low m-CT values showed no nodule changes. CONCLUSIONS: The m-CT value of GGO lesions is a risk factor associated with their future change. The interval of follow-up CT scanning or treatment policy should be determined considering the m-CT value.
    [Abstract] [Full Text] [Related] [New Search]