These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Cimetidine and ketotifen inhibit stimulated aggregation and histamine liberation from rabbit blood platelets.
    Author: Jancinová V, Nosál R.
    Journal: Agents Actions; 1989 Apr; 27(1-2):135-7. PubMed ID: 2473616.
    Abstract:
    The effect of cimetidine and ketotifen was studied on thrombin-stimulated rabbit platelet aggregation as well as on histamine and serotonin liberation. Both drugs inhibited the stimulation of platelets in a dose-dependent way. The effect of ketotifen on stimulated aggregation was about twice that of cimetidine. Stimulated histamine and serotonin liberation was more inhibited by ketotifen than by cimetidine. Both drugs inhibited the liberation of serotonin to a greater extent than that of histamine.
    [Abstract] [Full Text] [Related] [New Search]