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  • Title: Effects of channel-forming antibiotics on the membrane of skeletal muscle fibre.
    Author: Caffier G, Shvinka NE.
    Journal: Biomed Biochim Acta; 1989; 48(5-6):S552-7. PubMed ID: 2474291.
    Abstract:
    Gramicidin A, amphotericin B and nystatin increased the cation conductance and efflux rates from frog skeletal muscle fibres. Concerning gramicidin A, the characteristics tested are similar to those reported for BLM. Therefore, a channel formation like that in BLM is assumed for the muscle cell membrane. On the other hand, the kinetics of channel formation are different in muscle membrane and BLM. This suggests that the processes which limit the rate of channel formation are different.
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