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  • Title: PCR for detection of oseltamivir resistance mutation in influenza A(H7N9) virus.
    Author: Wang W, Song Z, Guan W, Liu Y, Zhang X, Xu L, Li J, Yuan Z, Hu Y.
    Journal: Emerg Infect Dis; 2014 May; 20(5):847-9. PubMed ID: 24751348.
    Abstract:
    Sensitive molecular techniques are needed for rapid detection of the R292K oseltamivir-resistant mutant of influenza A(H7/N9) virus strain to monitor its transmission and guide antiviral treatment. We developed a real-time reverse transcription PCR and single nucleotide polymorphism probes to differentiate this mutant strain in mixed virus populations in human specimens.
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