These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Ultrastructural localizations of beta-microseminoprotein, a prostate-specific antigen, in human prostate and sperm: comparison with gamma-seminoprotein, another prostate-specific antigen.
    Author: Ito Y, Tsuda R, Kimura H.
    Journal: J Lab Clin Med; 1989 Sep; 114(3):272-7. PubMed ID: 2475560.
    Abstract:
    Immunohistochemical localizations of beta-microseminoprotein and gamma-seminoprotein, which are prostate-specific antigens, were examined by light and electron microscopy with peroxidase-labeled antibody. In normal, hypertrophic, and neoplastic prostate glands, beta-microseminoprotein was found in glandular epithelium but not in stroma cells. beta-Microseminoprotein may be as useful as gamma-seminoprotein in the pathologic examination of prostatic diseases, especially in histogenic classification of tumors or metastatic tumors. In an immunoelectron microscopic study, the primary localizations of beta-microseminoprotein and gamma-seminoprotein in the cell were demonstrated to be secretory granule and lysosome, respectively, suggesting that beta-microseminoprotein is a secretory protein. Weak distributions of beta-microseminoprotein and gamma-seminoprotein were observed in rough endoplasmic reticulum and Golgi apparatus. In spermatozoa, beta-microseminprotein was found attached to the cell membrane of the head but not in the tail, and gamma-seminoprotein was not found at all.
    [Abstract] [Full Text] [Related] [New Search]