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  • Title: Sustained increase of serum creatine phosphokinase levels and progressive muscle abnormalities associated with raltegravir use during 32-week follow-up in an HIV-1 experienced patient on simplified HAART regimen, intolerant to protease inhibitors and abacavir: a case report.
    Author: Cirioni O, Weimer LE, Fragola V, Giacometti A, Gabrielli E, Marchionni E, Massella M, Barchiesi F.
    Journal: West Indian Med J; 2013; 62(4):377-9. PubMed ID: 24756601.
    Abstract:
    Sustained increase of serum creatine phosphokinase (CPK) concentrations and muscle abnormalities have been reported in patients taking raltegravir (RAL). In this report, we describe a case of sustained and asymptomatic increase of serum CPK concentrations associated with raltegravir, zidovudine, and lamivudine in an HIV-1 experienced patient with intolerance to protease inhibitor, abacavir and penicillin during 32 weeks of continuous drug monitoring.
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