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  • Title: [Indicators of humoral immunity in the surgical treatment of toxic goiter].
    Author: Kalaĭda LP, Ionov PSh, Vyrodov KS.
    Journal: Khirurgiia (Mosk); 1989 Jun; (6):11-3. PubMed ID: 2476581.
    Abstract:
    Changes in the content of gammaglobulins, immunoglobulins of all classes, and circulating immune complexes were revealed in 70 patients with toxic goiter given thyrostatic therapy, which may be evidence of disturbed humoral immunity. These disorders were most manifest in unstable compensation of toxicosis and in patients with ophthalmopathy. In patients with developed postoperative toxic reactions no specific changes in the immune status were detected in the preoperative period and no regularities allowing the prognostication of the development of a toxic reaction were revealed. Essential changes in humoral immunity values did not occur on the eighth postoperative day.
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