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  • Title: [Protective action of cytotoxic lymphocytes depending on the antigenic determinant composition of influenza virus hemagglutinin].
    Author: Berdinskikh MS, Kiseleva AS, Kosiakov PN.
    Journal: Biull Eksp Biol Med; 1989 Oct; 108(10):471-2. PubMed ID: 2480826.
    Abstract:
    The protective role of cytotoxic lymphocytes (CTL) in dependence on composition of antigenic determinants of hemagglutinin of influenza viruses H3N2 was studied. It was established that CTL do not exert protective effect under conditions of adoptive transfer, when there is one common antigenic determinant in hemagglutinins of the virus forming immunity. When all antigenic determinants in hemagglutinins of influenza viruses are identical, CTL-like antibodies represent one of the main factors of antivirus immunity.
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