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  • Title: [The effect of antihistamine preparations on the contraction of the isolated guinea pig ureter].
    Author: Kaminka ME, Zhirnikova ML.
    Journal: Farmakol Toksikol; 1989; 52(5):31-3. PubMed ID: 2480912.
    Abstract:
    The effect of antihistaminics on contractions of the isolated guinea pig ureter was studied. The ureter contractions induced by histamine were prevented by H1-blockers: pipolphen (promethazine), dimedrol (diphenhydramine), phencarol (quifenadine), suprastin (chloropyramine), cyproheptadine and H2-blockers: cimetidine, ranitidine. Electric stimulation-induced contractions were prevented by suprastin. Phencarol, tavegil, cimetidine, ranitidine didn't act on the contractions. The electrically induced contractions were potentiated by pipolphen, dimedrol, cyproheptadine.
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