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  • Title: [Lactate dehydrogenase and creatine kinase activity in nerve compression and myodystrophic syndromes of lumbar osteochondrosis].
    Author: Khabirov FA, Zhavoronkova GI, Khabirov RA.
    Journal: Lab Delo; 1989; (11):16-9. PubMed ID: 2481092.
    Abstract:
    The blood serum lactate dehydrogenase (LDH), creatine kinase (CK), and LDH isoforms activities have been measured in 103 patients with the compression neural and myodystrophic syndromes of lumbar osteochondrosis. The studies have revealed a relationship between the myodystrophic process severity and the intensity of LDH and CK ejection from the muscle into the blood, particularly in the trigger stage. The shift of LDH activity towards the predominance of slowly migrating isoforms augments and the total blood serum LDH and CK activities grow as the muscular syndrome progresses. These data permit a differentiation between the compression neural and the myodystrophic syndromes, as well as between the algic and the trigger stages of muscle involvement. Such a differentiation does not involve biopsy in many cases.
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