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  • Title: Squamous Cell Carcinoma of the Caruncle.
    Author: Sagili S, Yin V, Esmaeli B, O'Donnell B, Eckstein R, Malhotra R.
    Journal: Ophthalmic Plast Reconstr Surg; 2015; 31(4):e80-2. PubMed ID: 24814271.
    Abstract:
    Squamous cell carcinoma (SCC) of the lacrimal caruncle is a rare entity. The authors report the management and outcomes of 3 cases of caruncle SCC. Case 1 underwent wide margin surgical excision with adjuvant topical chemotherapy for a poorly differentiated SCC. He later developed regional lymph node metastasis and required modified radical neck dissection. Case 2 underwent wide margin surgical excision with cryotherapy and adjuvant topical chemotherapy for an invasive moderately differentiated SCC. She later developed a recurrence and underwent orbital exenteration. Case 3 was a moderately differentiated SCC treated with wide margin excision alone and had no recurrence during 5-year follow up. Careful surveillance of caruncle SCC is required, given the observed propensity for local recurrence and/or regional metastasis.
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