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  • Title: Dermal toxicity of hexachlorocyclohexane (HCH) in rabbit.
    Author: Dikshith TS, Raizada RB, Srivastava MK, Kumar SN, Kaushal RA, Singh RP, Gupta KP, Lakshmi KS.
    Journal: Indian J Exp Biol; 1989 Mar; 27(3):252-7. PubMed ID: 2481648.
    Abstract:
    Application of HCH (25 mg/kg) on dorsal, ventral and thigh regions of the skin of male rabbits resulted in poisoning and mortality of animals. Morphological changes in skin, liver, kidney, testes and cerebellum together with highly significant alterations in serum and liver enzymatic activity and residue in blood suggested that absorption of HCH and its toxicity could be severe when the pesticide comes in contact with the skin of thigh region of body.
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