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  • Title: A young man with primary prostatic extra-gastrointestinal stromal tumor: a rare case report and review of the literature.
    Author: Zhang ZH, Feng GW, Liu ZF, Qiao L, Zhang T, Gao C, Xu Y.
    Journal: Int J Clin Exp Pathol; 2014; 7(4):1764-70. PubMed ID: 24817976.
    Abstract:
    Mounting evidence demonstrates the presence of extragastrointestinal stromal tumor (EGIST) which originates from tissues outside the gastrointestinal (GI) tract and shares overlapping immunohistological features with gastrointestinal stromal tumor (GIST). GIST emanating from prostate is extremely rare. To our knowledge, there are only 3 definitely reported cases of primary prostatic EGIST. Herein, we report a case of prostatic EGIST in 31-year-old man with low urinary tract symptoms who was initially misdiagnosed as sarcoma of prostate. Imaging studies assist in determining the origin and location of EGIST. Immunohistochemical assessment (DOG-1, CD117, and CD34) helps in differentiating such lesion from other stromal tumors and in addressing an appropriate and optimal therapeutic strategy.
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