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  • Title: ANCA-mediated crescentic glomerulonephritis with linear deposition of IgG along the glomerular basement membrane.
    Author: Sangsiraprapha W, Truong L, Mandayam S.
    Journal: Saudi J Kidney Dis Transpl; 2014 May; 25(3):634-7. PubMed ID: 24821165.
    Abstract:
    Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides is an important cause of rapidly progressive glomerulonephritides (RPGN), and they are classically described as pauci-immune diseases as evidenced by the absence of immune deposits on immunofluoresence microscopy of the kidney biopsy. We report two patients with RPGN, pulmonary-renal syndrome, positive ANCA serology and linear Immunoglobulin G (IgG) staining on glomerular basement membrane in the absence of detectable anti-glomerular basement membrane (anti-GBM) antibodies in the serum.
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