These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Gombaspiroketals A-C, sesterterpenes from the sponge Clathria gombawuiensis.
    Author: Woo JK, Kim CK, Kim SH, Kim H, Oh DC, Oh KB, Shin J.
    Journal: Org Lett; 2014 Jun 06; 16(11):2826-9. PubMed ID: 24824092.
    Abstract:
    Gombaspiroketals A-C (1-3), tetracyclic sesterterpenes of a novel skeletal class, were isolated from the Korean marine sponge Clathria gombawuiensis. On the basis of the combined spectroscopic analyses, the structures of these compounds were determined to be highly rearranged sesterterpene spiroketal methoxyacetals (1 and 2) and a corresponding hemiacetal (3). The relative and absolute configurations were assigned by NOESY analysis and ECD calculations, respectively. These compounds exhibited moderate cytotoxicities and antibacterial activities.
    [Abstract] [Full Text] [Related] [New Search]