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  • Title: [A clinical and experimental study of longatsef].
    Author: Frolov AF, Trinus EK, Rudenko AA, Diadiun ST, Antonenko SV.
    Journal: Vrach Delo; 1989 Oct; (10):111-3. PubMed ID: 2482583.
    Abstract:
    Data are reported of the results of clinical trials of the therapeutic efficacy of longaceph--a drug of the new generation of cephalosporins with a long period of half-decay--in acute pneumonia complicating influenza in 42 patients. The sensitivity of 120 microbial strains to longaceph was also studied. It was established that cephalosporin possesses a high efficacy in diseases caused by gram-positive and gram-negative microorganisms. A high degree of sensitivity to longaceph was observed in pneumococci biogenous and Streptococcus viridans, Staphylococcus aureus and epidermidis, klebsiellae and escherichiae. A new property of longaceph was found, namely, its capacity to stimulate the formation of endogenous interferon.
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