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  • Title: Successful treatment of invasive zygomycosis based on a prompt diagnosis using molecular methods in a patient with acute myelogenous leukemia.
    Author: Yuda J, Kato K, Kikushige Y, Ohkusu K, Kiyosuke M, Sakamoto K, Oku S, Miyake N, Kadowaki M, Iino T, Tanimoto K, Takenaka K, Iwasaki H, Miyamoto T, Shimono N, Teshima T, Akashi K.
    Journal: Intern Med; 2014; 53(10):1087-91. PubMed ID: 24827491.
    Abstract:
    Zygomycosis is a lethal and invasive mold infection that is often associated with hematological malignancies. The keys for successful treatment include making a rapid diagnosis and appropriately administering antifungal agents. We herein report the early diagnosis of a case of zygomycosis in a patient with acute myeloid leukemia using a deoxyribonucleic acid sequence analysis. We successfully performed allogeneic hematopoietic stem cell transplantation with the use of high-dose liposomal amphotericin B and granulocyte transfusion.
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