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  • Title: Prevalence of Toxoplasma gondii and Toxocara canis among patients with uveitis.
    Author: Lim SJ, Lee SE, Kim SH, Hong SH, You YS, Kwon OW, Kim HS.
    Journal: Ocul Immunol Inflamm; 2014 Oct; 22(5):360-6. PubMed ID: 24833105.
    Abstract:
    PURPOSE: To investigate the prevalence of Toxoplasma gondii and Toxocara canis in patients with uveitis. METHOD: Patients with uveitis were examined. Serum antibodies to T. gondii and T. canis were tested by using enzyme-linked immunosorbent assay (ELISA). Polymerase chain reaction (PCR) was done using blood and aqueous humor (AH). RESULTS: 98 patients were enrolled. Mean age was 43.5 ± 13.2 years. Six patients were seropositive for T. gondii with the following pattern-anterior uveitis: 1; posterior uveitis with retinitis: 2; pan uveitis: 2. One patient had a positive result of PCR for T.gondii in AH, who showed pan uveitis. 23 patients were positive to serum IgG for T. canis with the following clinical manifestation-granuloma: 6; pigmented scar: 3; virtrits: 6-but none were PCR positive. CONCLUSION: T.gondii and T.canis are still one of the important causes of uveitis. Ocular toxocariasis is not an uncommon cause of uveitis even in adult.
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