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  • Title: Short-term outcomes of totally laparoscopic total gastrectomy: experience with the first consecutive 112 cases.
    Author: Tsunoda S, Okabe H, Obama K, Tanaka E, Hisamori S, Kinjo Y, Sakai Y.
    Journal: World J Surg; 2014 Oct; 38(10):2662-7. PubMed ID: 24838484.
    Abstract:
    INTRODUCTION: Although laparoscopic distal gastrectomy has become a viable treatment option for gastric cancer, laparoscopic total gastrectomy remains in limited use. PURPOSE: The present study was designed to evaluate the short-term outcomes of totally laparoscopic total gastrectomy (TLTG). METHODS: The records of 112 consecutive patients who underwent TLTG for gastric cancer between September 2006 and November 2012 were reviewed, and surgical outcomes were retrospectively investigated. RESULTS: Neoadjuvant chemotherapy was given to 21 patients (18.8 %). The degree of lymphadenectomy was D1+ in 83 patients (74.1 %) and D2 in 29 (25.9 %). The operation time was 359 min, median intraoperative blood loss was 85 ml, and median total number of harvested lymph nodes was 64. Grade II or higher postoperative complications developed in 25 patients (22.3 %). On univariate analysis, pathologic stages IB to IV (versus stage IA) overlapped esophagojejunostomy (versus functional end-to-end esophagojejunostomy) and operation time >360 min (versus ≤360 min) were related to postoperative morbidity. In the multivariate analysis, operative time and pathologic stage were independent risk factors for postoperative complications. CONCLUSIONS: TLTG is feasible and can be performed with acceptable postoperative morbidity. A longer operating time and more advanced pathologic stage were significantly associated with higher postoperative morbidity.
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