These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Long-term psychological effects of childhood leukemia and its treatment.
    Author: Jannoun L, Chessells JM.
    Journal: Pediatr Hematol Oncol; 1987; 4(4):293-308. PubMed ID: 2484651.
    Abstract:
    We report the results of a 5-year follow-up of the cognitive development of 19 survivors of acute lymphoblastic leukemia, all of whom received 24 Gy cranial irradiation and a course of intrathecal methotrexate. Assessment was made before radiotherapy and annually thereafter. Cognitive impairment was found to be transient in children who did not manifest somnolence who were under 5 years at the time of treatment. Despite having normal IQs and normal CT scans, 9 of 18 survivors in continuous complete remission were having learning problems at school 5 years after diagnosis. Assessment of their intellectual and memory functions revealed that as compared with matched healthy children, patients had lowered IQs but also had a specific auditory learning deficit independent of IQ. Long-term memory was found to be impaired for verbal auditory but not for verbal visual material. Results are discussed in terms of possible remediation of the learning disability.
    [Abstract] [Full Text] [Related] [New Search]