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  • Title: α-Glucosidase inhibitors from the stems of Embelia ribes.
    Author: Dang PH, Nguyen HX, Nguyen NT, Le HN, Nguyen MT.
    Journal: Phytother Res; 2014 Nov; 28(11):1632-6. PubMed ID: 24849650.
    Abstract:
    From the ethyl acetate extract of the stems of Embelia ribes (Myrsinaceae), a new alkenylresorcinol, embeliphenol A (1), together with 11 known compounds have been isolated. Their structures were elucidated on the basis of spectroscopic data. All compounds possessed significant α-glucosidase inhibitory activity in a concentration-dependent manner, except for 2 and 9. Compounds 1, 3-6, 8, and 12 showed more potent inhibitory activity, with IC50 values ranging from 10.4 to 116.7 μM, than that of a positive control acarbose (IC50 , 214.5 μM).
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