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  • Title: Nanoparticle-delivered quercetin for cancer therapy.
    Author: Men K, Duan X, Wei XW, Gou ML, Huang MJ, Chen LJ, Qian ZY, Wei YQ.
    Journal: Anticancer Agents Med Chem; 2014; 14(6):826-32. PubMed ID: 24851877.
    Abstract:
    Quercetin, a natural protective bioflavonoid, possesses diverse pharmacologic effects, such as antioxidant, anti-inflammatory, anti-proliferative, and anti-angiogenic activities. Recently, quercetin's effect in cancer prevention and treatment was recognized. However, the poor water solubility and low-bioavailability of quercetin limit its clinical use in cancer therapy. Nanotechnology provides a method to create novel formulations for hydrophobic drug. Nanoparticles-delivered quercetin has attracted many attentions for its enhanced anticancer potential and promising clinical application. This review will discuss the application of nanotechnology in quercetin delivery for cancer therapy.
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