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  • Title: A fast automated screening method for the detection of blood transfusion in sports.
    Author: Leuenberger N, Ansermet C, Pottgiesser T, Baume N, Robinson N, Saugy M, Schumacher YO.
    Journal: Drug Test Anal; 2014; 6(11-12):1141-3. PubMed ID: 24853344.
    Abstract:
    Currently, there is no simple direct screening method for the misuse of blood transfusions in sports. In this study, we investigated whether the measurement of iron in EDTA-plasma can serve as biomarker for such purpose. Our results revealed an increase of the plasma iron level up to 25-fold 6 h after blood re-infusion. The variable remained elevated 10-fold one day after the procedure. A specificity of 100% and a sensitivity of 93% were obtained with a proposed threshold at 45 µg/dL of plasma iron. Therefore, our test could be used as a simple, cost effective biomarker for the screening for blood transfusion misuse in sports.
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