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  • Title: Biological effects of emissions from resistance spot welding of zinc-coated material after controlled exposure of healthy human subjects.
    Author: Gube M, Kraus T, Lenz K, Reisgen U, Brand P.
    Journal: J Occup Environ Med; 2014 Jun; 56(6):673-7. PubMed ID: 24854261.
    Abstract:
    OBJECTIVE: Do emissions from a resistance spot welding process of zinc-coated materials induce systemic inflammation in healthy subjects after exposure for 6 hours? METHODS: Twelve healthy male subjects were exposed once for 6 hours either to filtered ambient air or to welding fume from resistance spot welding of zinc-coated material (mass concentration approximately 100 μg m). Biological effects were measured before, after, and 24 hours after exposure. RESULTS: At the concentrations used in this study, however, the suspected properties of ultrafine particles did not lead to systemic inflammation as reflected by high-sensitivity C-reactive protein or other endpoint parameters under consideration. CONCLUSIONS: Ultrafine particles from a resistance spot welding process of zinc-covered materials with a number concentration of about 10 cm and a mass concentration of about 100 μg m did not induce systemic inflammation.
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