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  • Title: Methysergide-induced psychosis: case report with long-term follow-up.
    Author: Skorzewska A, Lal S.
    Journal: Neuropsychobiology; 1989; 22(3):125-7. PubMed ID: 2485859.
    Abstract:
    Methysergide, a congener of LSD and potent serotonin (5-HT) antagonist, induced a florid transient psychosis resembling an LSD psychosis in a patient with spasmodic torticollis with a family history of schizophrenia. Thirteen years later he developed a major depression. A variety of other drug challenges and treatments for his torticollis had no psychotomimetic effect. Blockade of 5-HT receptors may subserve methysergide-induced psychosis.
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