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  • Title: Uncommon side effect with a commonly used targeted agent: sunitinib-induced nephrotic syndrome in a patient with metastatic renal cell carcinoma.
    Author: Quintyne KI, Neenan T, Casserly L, Gupta R.
    Journal: BMJ Case Rep; 2014 May 28; 2014():. PubMed ID: 24872478.
    Abstract:
    The authors report the case of a 67-year-old woman with metastatic renal cell carcinoma (RCC) without prior nephrectomy, who had received long-term exposure (38 months) to the oral multi-targeted tyrosine kinase inhibitor (TKI), sunitinib. She had a sustained clinical and radiological response to her therapy, but had this therapy discontinued due to the rare development of nephrotic syndrome.
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