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  • Title: A folate receptor-specific activatable probe for near-infrared fluorescence imaging of ovarian cancer.
    Author: Lee H, Kim J, Kim H, Kim Y, Choi Y.
    Journal: Chem Commun (Camb); 2014 Jul 18; 50(56):7507-10. PubMed ID: 24887157.
    Abstract:
    We have developed a folate receptor-specific activatable probe for in vivo near-infrared fluorescence imaging of ovarian cancer. This probe becomes highly fluorescent only when its linker is cleaved by a tumor-associated lysosomal enzyme cathepsin B after internalization into folate receptor-positive cancer cells.
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