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  • Title: Immunodiagnosis of human and porcine cysticercosis. Detection of antibodies and parasite products.
    Author: Correa MD, Plancarte A, Sandoval MA, Rodriguez-del-Rosal E, Meza-Lucas A, Flisser A.
    Journal: Acta Leiden; 1989; 57(2):93-9. PubMed ID: 2489007.
    Abstract:
    In this paper we report the immunodiagnosis of cysticercosis by the detection of antibodies in the cerebrospinal fluid (CSF) of patients, by standard enzyme immunoassay (EIA) which gave 90% sensitivity. We are also showing the results obtained with a double homologous polyclonal or monoclonal antibody based EIA that detects parasite products: we analysed CSF of patients and obtained sensitivities ranging from 14% to 75% for single antibody systems and 90% when analysing the samples with two or three systems simultaneously. The sera of infected pigs were also evaluated; with one monoclonal antibody we could detect 79% of positive samples. The good results obtained encourage the standardization and improvement of the technique for diagnostic as well as for epidemiologic purposes.
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