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  • Title: Clinical and laboratory characteristics of central nervous system herpes simplex virus infection in neonates and young infants.
    Author: Kotzbauer D, Andresen D, Doelling N, Shore S.
    Journal: Pediatr Infect Dis J; 2014 Nov; 33(11):1187-9. PubMed ID: 24892851.
    Abstract:
    We reviewed the characteristics of infants <3 months of age with central nervous system herpes simplex virus infection at our institution. Twenty-six cases were identified. The age range was 4-73 days. Most infants presented with fever, seizure activity and skin lesions. The blood herpes simplex virus polymerase chain reaction was positive in 91% of patients tested. Suppressive oral acyclovir therapy was likely helpful in preventing disease recurrence.
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