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Title: Peptide p160-coated silica nanoparticles applied in photodynamic therapy. Author: Yang Y, Wang A, Jia Y, Brezesinski G, Dai L, Zhao J, Li J. Journal: Chem Asian J; 2014 Aug; 9(8):2126-31. PubMed ID: 24895152. Abstract: Peptide p160-conjugated mesoporous silica nanoparticles (MSN) were fabricated and loaded with photosensitizer hypocrellin B (HB). The results indicate that the nanocomposites have better selectivity for cancer cells and higher cytotoxicity in photodynamic therapy in vitro. The nanocomposites can be used as a novel candidate in photodynamic therapy. This may be a general and promising method to modify nanoparticles to improve their cell affinity.[Abstract] [Full Text] [Related] [New Search]