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  • Title: Severe lactic acidosis and multiorgan failure due to thiamine deficiency during total parenteral nutrition.
    Author: Ramsi M, Mowbray C, Hartman G, Pageler N.
    Journal: BMJ Case Rep; 2014 Jun 03; 2014():. PubMed ID: 24895398.
    Abstract:
    A 16-year-old perioperative paediatric patient presented with refractory lactic acidosis and multiorgan failure due to thiamine-deficient total parenteral nutrition during a recent national multivitamin shortage. Urgent empiric administration of intravenous thiamine resulted in prompt recovery from this life-threatening condition. Despite readily available treatment, a high index of suspicion is required to prevent cardiovascular collapse and mortality.
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