These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Regioselective synthesis of 3,4,5-trisubstituted 2-aminofurans.
    Author: Huynh TN, Retailleau P, Denhez C, Nguyen KP, Guillaume D.
    Journal: Org Biomol Chem; 2014 Jul 28; 12(28):5098-101. PubMed ID: 24931912.
    Abstract:
    Three series of methyl 5-substituted 2-aminofuran-4-keto-3-carboxylates have been prepared following a multicomponent reaction strategy by the addition of an isocyanide to 4-oxo-2-butynoate in the presence of an aldehyde. The cycloaddition regioselectivity is generally high (>95%) but decreases when an electron-rich substituent is located at the butynoate 4-position.
    [Abstract] [Full Text] [Related] [New Search]