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  • Title: [Composition and antitumor activities of essential oil from the fruits of Dasymaschalon trichophorum].
    Author: Li XB, Chen GY, Song XP, Han CR, Zheng CJ.
    Journal: Zhong Yao Cai; 2013 Nov; 36(11):1786-8. PubMed ID: 24956819.
    Abstract:
    OBJECTIVE: To study the chemical components and antitumor activities of essential oil from the fruits of Dasymaschalon trichophorum. METHODS: The essential oil from the fruits of Dasymaschalon trichophorum was extracted by steam-stilling and analyzed by GC-MS. The inhibitory effect of extract of Dasymaschalon trichophorum on SPCA-1,BEL-7402, SGC-7901 and K-562 cell proliferation was assayed using the MTU. RESULTS: GC-MS result showed that there were 55 peaks and 30 compounds were identified which weighed 74.98%. The major components were nerolidol (19.887%), caryophyllene (16.714%) and beta-myrcene (9.29%). The essential oil exhibited strong antitumor activity against SPCA-1 human tumor cell line with IC50 value of 6.61 microg/mL. CONCLUSION: This experiment provides scientific foundation for further utilization of Dasymaschalon trichophorum.
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