These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Bovine lens aldose reductase: identification of two enzyme forms.
    Author: Del Corso A, Barsacchi D, Camici M, Garland D, Mura U.
    Journal: Arch Biochem Biophys; 1989 May 01; 270(2):604-10. PubMed ID: 2495769.
    Abstract:
    Two structurally different forms of bovine lens aldose reductase have been identified. Freshly prepared lens extracts contain an unactivated "b form" (ARb) which is sensitive to inhibition by Sorbinil. Upon incubation of the extracts with oxygen radical generating systems, ARb is converted to a more active "a form" (ARa), which is not inhibited by Sorbinil. ARa and ARb were purified to electrophoretic homogeneity.
    [Abstract] [Full Text] [Related] [New Search]