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  • Title: The 'breakpoint' test, a new statistical method for studying progression of chronic renal failure.
    Author: Zoccali C, Postorino M, Martorano C, Salnitro F, Maggiore Q.
    Journal: Nephrol Dial Transplant; 1989; 4(2):101-4. PubMed ID: 2496349.
    Abstract:
    The application of a new statistical method ('breakpoint' test) to the study of the progression of chronic renal failure is described. This test establishes whether the best fit of a series of GFR measurements is linear or broken. Such an approach avoids the analytical constraint of the time of intervention assumed by other methods. Re-analysis by this test of previous studies of low-protein diet suggests that in some cases the effect of the dietary regimen has been overemphasized.
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