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  • Title: [Participation of alveolar macrophages in the catabolism of fibrinogen and fibrin].
    Author: Zubairov DM, Subkhankulova FB, Evranova GB.
    Journal: Biull Eksp Biol Med; 1989 Mar; 107(3):335-7. PubMed ID: 2496767.
    Abstract:
    The penetration of FITC-fibrinogen in rabbit alveolar macrophages depends on Ca2+ and Mg2+. Therefore there is reason to believe the process is not restricted only by diffusion on concentration gradient, but pinocytosis takes place, which depends Ca2+. The absorption of FITC-label from fibrin by alveolar macrophages is more slow than from fibrinogen. Soluble high-molecular products of fibrin degradation can be trapped by pinocytosis. On the basis of such studies it was assumed that degradation of fibrin proceeds parietally.
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