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  • Title: Multifocal electroretinograms in Stargardt's disease/fundus flavimaculatus.
    Author: Kuniyoshi K, Terasaki H, Arai M, Hirose T.
    Journal: Ophthalmologica; 2014; 232(2):118-25. PubMed ID: 24970593.
    Abstract:
    PURPOSE: To determine whether the characteristics of multifocal electroretinograms (mfERGs) were correlated with the ophthalmic appearance of the fundus in patients with Stargardt's disease/fundus flavimaculatus (SFF). METHODS: Full-field ERGs, mfERGs, and general ophthalmic examinations were performed on 49 eyes with SFF. RESULTS: The SFF patients were divided into four subtypes according to the classification of Noble and Carr [Arch Ophthalmol 1979;97:1281-1285]. The patients with type 1 SFF had severely reduced mfERGs in the macular area and reduced and delayed responses in the mid-periphery. The type 2 SFF patients had reduced but recordable mfERGs from the center of the macula with more depressed responses in the paramacular area, and the type 3 SFF patients had reduced and delayed mfERGs both in the macula and periphery. The patients with type 4 SFF had normal mfERGs in the macular area and delayed responses in all outer zones. CONCLUSIONS: These mfERG findings indicate that each subtype of SFF has unique characteristics corresponding to the abnormal retinal functions.
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