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  • Title: 99mTc(Cu)-mannitol complex: a new agent for dynamic renal function studies.
    Author: Chauhan UP, Chander J, Mishra P, Sarin RC, Narayanan RV, Singh B.
    Journal: Int J Rad Appl Instrum B; 1989; 16(3):283-9. PubMed ID: 2497090.
    Abstract:
    Mannitol has been labeled with 99mTc by using cuprous chloride as a reducing agent. Blood and kidney clearance of 99mTc(Cu)-mannitol was slightly faster than that of 99mTc(Sn)-DPTA in rat and maximum radioactivity ratio of kidneys to blood was 84.6 at 5 min. A comparative study of 99mTc(Cu)-mannitol, 99mTc(Sn)-DTPA was made in rabbits by taking serial images of kidneys and bladder with a gamma camera. Results show superiority of 99mTc(Cu)-mannitol over other agents for dynamic renal function studies.
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