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  • Title: Calcium and magnesium disorders.
    Author: Goff JP.
    Journal: Vet Clin North Am Food Anim Pract; 2014 Jul; 30(2):359-81, vi. PubMed ID: 24980727.
    Abstract:
    Hypocalcemia is a clinical disorder that can be life threatening to the cow (milk fever) and predisposes the animal to various other metabolic and infectious disorders. Calcium homeostasis is mediated primarily by parathyroid hormone, which stimulates bone calcium resorption and renal calcium reabsorption. Parathyroid hormone stimulates the production of 1,25-dihydroxyvitamin D to enhance diet calcium absorption. High dietary cation-anion difference interferes with tissue sensitivity to parathyroid hormone. Hypomagnesemia reduces tissue response to parathyroid hormone.
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