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  • Title: Clinical utility of the modified Glasgow prognostic score in patients with advanced head and neck cancer.
    Author: Nakayama M, Tabuchi K, Hara A.
    Journal: Head Neck; 2015 Dec; 37(12):1745-9. PubMed ID: 24989115.
    Abstract:
    BACKGROUND: The purpose of this study was to evaluate the prognostic potential of the modified Glasgow prognostic score (mGPS), known to reflect the degree of tumor-associated inflammation and cancer cachexia, in patients with advanced head and neck cancer. METHODS: Patients with advanced head and neck cancer treated at the University of Tsukuba Hospital between January 2002 and December 2011 were retrospectively evaluated. They were categorized by their mGPS. RESULTS: A total of 210 patients were enrolled in this study. Patients with an mGPS of 0 had better overall survival and disease-free survival than did those with an mGPS of 1 or 2. Multivariate analysis revealed that the mGPS was a significant risk factor for overall survival and disease-free survival. CONCLUSIONS: Our results suggest that the mGPS is useful for predicting outcome in patients with advanced head and neck cancer and should be included in their routine clinical assessment.
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