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  • Title: [Biological availability of glycerol trinitrate after sublingual administration].
    Author: Rietbrock N, Herling C, Muck B.
    Journal: Arzneimittelforschung; 1989 Feb; 39(2):267-9. PubMed ID: 2499342.
    Abstract:
    The relative bioavailability of a glyceryl trinitrate (GTN) spray (Nitro-Corangin Spray) compared to that of another GTN Spray was evaluated in 12 healthy male volunteers using an open, randomized cross-over design with two treatment phases. The parameters Cmax, tmax and AUC0-1 showed no statistically significant differences between the two treatments. It is concluded that the two GTN-Sprays may be considered bioequivalent.
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