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  • Title: Localizing viruses in their insect vectors.
    Author: Blanc S, Drucker M, Uzest M.
    Journal: Annu Rev Phytopathol; 2014; 52():403-25. PubMed ID: 24996011.
    Abstract:
    The mechanisms and impacts of the transmission of plant viruses by insect vectors have been studied for more than a century. The virus route within the insect vector is amply documented in many cases, but the identity, the biochemical properties, and the structure of the actual molecules (or molecule domains) ensuring compatibility between them remain obscure. Increased efforts are required both to identify receptors of plant viruses at various sites in the vector body and to design competing compounds capable of hindering transmission. Recent trends in the field are opening questions on the diversity and sophistication of viral adaptations that optimize transmission, from the manipulation of plants and vectors ultimately increasing the chances of acquisition and inoculation, to specific "sensing" of the vector by the virus while still in the host plant and the subsequent transition to a transmission-enhanced state.
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