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  • Title: [Detection of typhi antibodies by latex agglutination].
    Author: Geng Y.
    Journal: Zhonghua Yu Fang Yi Xue Za Zhi; 1989 Mar; 23(2):96-8. PubMed ID: 2500317.
    Abstract:
    A latex test for immunodiagnosis of murine typhus, using erythrocyte-sensitizing substance from Rickettsia prowazekii absorbed to latex particles, has been developed. The test was evaluated with a total of 234 healthy person and non-typhus patient sera, 89 single and 63 paired typhus patient sera. The positive rate was 92.1% for paired and 80.9% for single sera from patients with typhus. The test gave results consistent with those given by the microimmunofluorescence (Micro-IF) and microagglutination (MA) tests. The sensitivity of the test was higher than Weil-Felix (P less than 0.05) test. This test was simple, rapid, sensitive and specific.
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