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  • Title: Tuberculosis of ultralong segmental thoracic and lumbar vertebrae treated by posterior fixation and cleaning of the infection center through a cross-window.
    Author: Gao Z, Wang M, Zhu W, Zheng G, Meng Y.
    Journal: Spine J; 2015 Jan 01; 15(1):71-8. PubMed ID: 25011095.
    Abstract:
    BACKGROUND CONTEXT: Surgical treatment of thoracolumbar tuberculosis (TB) aims at spinal cord decompression, focus debridement, spine stability, and deformity correction. However, several problems exist in treating multiple segmental thoracolumbar TB, including reducing surgical trauma with effective incision exposure; ensuring the effective long-armed fixation, and maintaining the possibility for revisionary surgery in cases of treatment failure. PURPOSE: To investigate the clinical efficacy and surgical technique of the single posterior midline approach for screw-rod fixation and debridement through the sacrospinalis muscle outer cross-window to treat multiple segmental thoracolumbar spinal TB. STUDY DESIGN: A retrospective cohort study. PATIENT SAMPLE: A group of 17 patients with spinal TB after surgical treatment, with a mean follow-up of 27.9 months (range, 18-48 months). OUTCOME MEASURES: Neurologic recovery, Cobb angle, and graft union assessed by the Moon standard. METHODS: This study was approved by the local ethical committee and recruited patients from January, 2005 to January, 2011. We used a posterior midline incision for internal fixation of a pedicle screw system in the gap of the longissimus and spinal multifidus. Anterior lesion debridement and interbody fusions were performed through bilateral cross-windows in the outer edge of the sacrospinalis muscle. Using this technique, we treated 17 patients (10 men; aged 19 to 68 years; mean 39.8 years) with spinal TB involving more than four vertebrae. Nerve damage was classified by the Frankel classification. All patients were treated with regular anti-TB chemotherapy and were followed for 18 to 48 (mean: 27.9 months) months. RESULTS: The mean (range) for operative time was 4.7 (3.6-6.3) hours, for blood loss during surgery was 1,100 (850-2,300) mL, and for time of interbody fusion was 6.3 (4 to 11) months. The Cobb angle correction rate is 67.1%. Nine of 11 patients' neurologic function returned to normal, which was statistically significant (p=.004). There was no TB recurrence or internal fixation failure. CONCLUSIONS: Combined with anti-TB chemotherapy, the discussed surgical technique can show improved lesion clearance, decompression of the anterior aspect of the spine, bone graft fusion, internal fixation of outside lesions, drainage and lead to positive treatment outcomes.
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