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  • Title: Successful treatment of superior vena cava syndrome with urokinase in an infant with a central venous catheter.
    Author: Caglar MK, Tolboom J.
    Journal: Helv Paediatr Acta; 1989 Jun; 43(5-6):483-6. PubMed ID: 2501237.
    Abstract:
    An infant with superior vena cava syndrome due to thrombus formation in the superior vena cava, sourced from a central venous line, was treated with urokinase. It was used in a loading dose of 250,000 units/1.73 m2/15 min, followed by continuous infusion of 125,000 units/1.73 m2/h for three days. After two days of urokinase treatment, the clinical signs of superior vena cava syndrome completely disappeared. No bleeding complication was observed.
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