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  • Title: [Integration and amplification of plasmid DNA in the Bacillus subtilis chromosome].
    Author: Shevchenko TN, Timashova EO, Fomin VV, Telegeev GD.
    Journal: Tsitol Genet; 1989; 23(2):53-8. PubMed ID: 2502873.
    Abstract:
    Some Bacillus subtilis strains demonstrate a high degree of pHV14 and pP1251 plasmid integration into the chromosome (1.10(-1]. According to the data of genetical analysis the plasmids are integrated into several regions of the same chromosome. A significant plasmid amplification in the composition of chromosome is observed when breeding on an increasing chloramphenicol concentration (20-300 micrograms/ml). Both tandem repetitions and single plasmid DNA copies and their fragments are found in the bacterial chromosomal DNA.
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